Small cell lung carcinoma represents a group of 5 HTP highly malignant tumors giving rise to early and widespread metastasis at the time of diagnosis.However, the pancreas is a relatively infrequent site of metastasis by this neoplasm, and there are only occasional reports on its fine needle aspiration (FNA) cytology diagnosis.A 66-year-old man presented with extensive mediastinal lymphadenopathy and a mass in the pancreatic tail.
Ultrasound-guided FNA smears from the pancreatic mass contained small, round tumor cells with extensive nuclear molding.The cytodiagnosis was metastatic small cell carcinoma.Immunocytochemical staining showed that a variable number of neoplastic cell were positive for cytokeratin, chromogranin A, neurone-specific enolase and synaptophysin but negative for leukocyte common antigen.
The trans-bronchial needle aspiration was non-diagnostic, but biopsy was suspicious of a small cell carcinoma.This case represents a rare metastatic lesion in the Sailing Skorts pancreas from small cell lung carcinoma, diagnosed by FNA cytology.